The BRCAct tumour testing service
The BRCAct Tumour testing service is offered at specified collaboration laboratories for patients who meet the eligibility criteria.
- The patient has newly diagnosed, advanced (FIGO stages III and IV) high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer
- The patient has relapsed ovarian cancer (includes fallopian tube and primary peritoneal cancers) and has already received one treatment for their disease [i.e. patient is second line])
- The patient has relapsed ovarian cancer (includes fallopian tube and primary peritoneal cancers) and has already received at least two treatments for their disease [i.e. patient is third line or beyond])
The BRCAct Tumour testing process involves several logistical steps, starting at the local oncology department, through the local pathology department and the collaborative laboratory.
How to use this service
You can access the service by completing the relevant tumour BRCA testing form (below) and sending this, along with the tumour sample, to one of the BRCAct collaboration laboratories. The results should be returned within 4 weeks after receipt of patient form and sample. The BRCAct collaboration laboratories offering this service are:
Genomic Diagnostics Laboratory, Manchester
Genomic Diagnostics Laboratory Genetic Medicine (6th Floor)
Genomic Diagnostic Laboratory, Manchester
St. Mary's Hospital Oxford Road
Manchester M13 9WL
In case of queries contact
Tel: 0161 276 3265/6122
Clinical Genomics, Molecular Diagnostics, The Royal Genomics, The Royal Marsden
Centre for Molecular Pathology
The Royal Marsden NHSFT
15 Cotswold Road, Sutton
Surrey SM2 5NG
Tel: 020 8915 6565
Bristol Genetics Laboratory*
Tel: 0117 4146168
*Bristol will only be taking samples from across the South West of England
For NHS clinicians based in Scotland the BRCAct Service will be supporting tumour BRCA testing for patients with newly diagnosed ovarian cancer via:
- The West of Scotland Centre of Genomic Medicine at the Queen Elizabeth University hospital in Glasgow.
- Accepting NHS samples from West Scotland.
- The Genetics and Molecular Pathology Laboratory at the Aberdeen Royal Infirmary in Aberdeen.
- Accepting NHS samples from East Scotland.
Depending on your location in Scotland please contact the respective lab for the BRCA test request forms, the local pathway guidance and any other information requests.
Genetic testing and pathway queries - Glasgow:
West of Scotland Centre for Genomic Medicine, Glasgow
Level 2B laboratory medicine
Queen Elizabeth University Hospital
1345 Govan Road
Genetic testing and pathway queries - Aberdeen:
Laboratory Genetics and Molecular Pathology, Aberdeen
North East Genetics Services
Head of Germline Service - Dawn O'Sullivan