BRCA Testing

For women with ovarian cancer, early identification of BRCA mutations can help determine the most appropriate treatment plan, and if the mutation is germline, can also support identification of family members at risk, and reduce future cancers through potential interventions.1–3

Whilst germline BRCA testing for women with ovarian cancer is now commissioned by NHS England, funding for tumour BRCA testing remains limited.4,5 Therefore, to support identification of these women, AstraZeneca is providing a tumour BRCA testing service  at certain sites in the UK for patients who meet the eligibility criteria.

Here you can find out more about BRCA testing, what the AstraZeneca tumour BRCA testing service is and how you can access it.

Tumour BRCA testing service

AstraZeneca are offering a tumor BRCA testing service at specified collaboration laboratories for patients who meet the eligibility criteria. This is to ensure patients who have a somatic BRCAm are identified and are given the opportunity to access treatments such as Lynparza capsules.

How to access the service

You can access the service by completing the relevant AstraZeneca tumour BRCA testing form (below) and sending this, along with the tumour sample, to one of the AstraZeneca collaboration laboratories. The results should be returned 4-6 weeks after receipt of patient form and sample. The three collaboration laboratories AstraZeneca are currently working with to offer this service are:

All Wales Genetic Laboratory, Cardiff
All Wales Genetics Laboratory
Institute of Medical Genetics
University Hospital of Wales
Cardiff CF14 4XW
Tel: 02920 742641

Genomic Diagnostic Laboratory, Manchester
Genomic Diagnostics Laboratory Genetic Medicine (6th Floor)
St. Mary’s Hospital Oxford Road
Manchester M13 9WL
Tel: 0161 276 3265/6122

Clinical Genomics, The Royal Marsden 
Centre for Molecular Pathology
The Royal Marsden NHSFT
15 Cotswold Road, Sutton
Surrey SM2 5NG
Tel: 020 8915 6565

How to access the service
How to access the service