LOKELMATM Sodium Zirconium Cyclosilicate

SWIFT* K+ REDUCTION AFTER ONE HOUR.1,2
SUSTAINED K+ CONTROL FOR UP TO ONE YEAR
WHEN USED AS A MAINTENANCE THERAPY.†1
NOW IN YOUR HANDS.
New, highly-selective LOKELMA (sodium zirconium cyclosilicate)
is indicated for the treatment of hyperkalaemia in adult patients1

*In an emergency situation, standard of care should be used in line with local or national guidelines
Clinical trials with LOKELMA have not included exposure longer than one year

Product Information

Prescribing LOKELMA

LOKELMA is a powder for oral suspension and is intended for oral use.1

To administer, mix LOKELMA with 3 tablespoons (a total of 45 mL) of water

  • The tasteless liquid should be drunk while still cloudy1
  • If the powder settles, the water should be stirred again1
  • It should be ensured that all of the content is taken1
Empty LOKELMA sachet into about 3 tablespoons of water
Empty LOKELMA sachet into about 3 tablespoons of water

LOKELMA can transiently increase gut pH by absorbing hydrogen ions, which can lead to changes in solubility and absorption kinetics for co-administered drugs with pH-dependent bioavailability. Therefore, LOKELMA should be administered at least 2 hours after or 2 hours before oral medications with gastric pH-dependent bioavailability.1

Drug–drug interactions are summarised in the section ‘drug interactions’ below, refer to prescribing information before use or SPC for further information.

Additional administration information:

  • Tasteless and odourless1,3
  • May be taken with many other medications1
  • May be taken with or without food1
  • No special conditions for storage1