Calibre What Science Can Do

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Expert opinion

Listen to expert authors on clinical studies 


Approaches to patient selection for long-term dual antiplatelet therapy (DAPT)
Dr Marc Bonaca


Dr Marc Bonaca 

Marc P. Bonaca, MD, MPH is a Cardiologist and Vascular Medicine Specialist who serves as the Executive Director of CPC Clinical Research and CPC Community Health which is an Academic Research Organization created by and affiliated with the University of Colorado Anschutz Medical Campus. He is the Director of Vascular Research and an Associate Professor of Medicine at the University of Colorado School of Medicine and the inaugural holder of the William R. Hiatt Endowed Chair in Cardiovascular Research. CPC is a core resource of the University of Colorado research and community outreach infrastructure.

After completion of his training he joined the faculty of the Cardiovascular Division and Vascular Medicine section of Brigham and Women’s Hospital and Harvard Medical School and became an Investigator at the TIMI Study Group. At Brigham and Women’s Hospital, Boston, MA, USA, he founded the Aortic Syndrome Program and served as the Medical Director of the Aortic Center. At the TIMI Study Group he was the Chairman of the TIMI Safety Desk and oversaw pharmacovigilance activities for more than 8 large, multinational clinical trials. At TIMI he was an investigator on the TRA2P-TIMI 50 trial, co-Principal Investigator of the PEGASUS-TIMI 54 trial, co-investigator and United States National Lead Investigator of the DECLARE-TIMI 58 trial, and Principal Investigator of the REAL-TIMI 63B trial. At TIMI he led investigation in multiple datasets evaluating vascular outcomes including major adverse limb events and venous thromboembolism. He is currently the Center Director and Clinical Project Principal Investigator of the Brigham and Women’s Hospital and Dartmouth Hitchcock Center in the American Heart Association Strategically Focused.